{"id":76367,"date":"2023-07-13T02:20:50","date_gmt":"2023-07-12T23:20:50","guid":{"rendered":"https:\/\/www.haberegider.com\/blog\/?p=76367"},"modified":"2023-07-13T02:20:50","modified_gmt":"2023-07-12T23:20:50","slug":"japonyada-arastirmacilar-yumurtalik-kanserini-erken-teshis-edebilecek-proteinler-kesfetti","status":"publish","type":"post","link":"https:\/\/www.haberegider.com\/blog\/japonyada-arastirmacilar-yumurtalik-kanserini-erken-teshis-edebilecek-proteinler-kesfetti\/","title":{"rendered":"Japonya’da ara\u015ft\u0131rmac\u0131lar, yumurtal\u0131k kanserini erken te\u015fhis edebilecek proteinler ke\u015ffetti"},"content":{"rendered":"

Japonya’da ara\u015ft\u0131rmac\u0131lar, yumurtal\u0131k kanserinin erken ve daha kolay te\u015fhis edilmesi i\u00e7in \u00e7al\u0131\u015fmalarda yard\u0131mc\u0131 olacak \u00fc\u00e7 zar protein ke\u015ffetti.<\/h4>\n

Technology Networks internet sitesinin haberine g\u00f6re, Japonya’daki Nagoya \u00dcniversitesinden bilim insanlar\u0131, yumurtal\u0131k kanserinin te\u015fhis y\u00f6ntemlerinin geli\u015ftirilmesine dair umut veren bir ara\u015ft\u0131rma yapt\u0131.<\/p>\n

\u00dcniversite b\u00fcnyesindeki \u0130leri Ara\u015ft\u0131rma Enstit\u00fcs\u00fcnden Dr. Akira Yokoi ve Dr. Mayu Ukai liderli\u011finde y\u00fcr\u00fct\u00fclen ara\u015ft\u0131rmada, yumurtal\u0131k kanseri vakalar\u0131n\u0131n y\u00fczde 75’ini olu\u015fturan y\u00fcksek dereceli ser\u00f6z karsinom (HGSC) alt tipine sahip hastalardan kanser h\u00fccrelerinin \u00e7eperinde bulunan vezik\u00fcller (EVler) al\u0131nd\u0131.<\/p>\n

Hastalardan al\u0131nan k\u00fc\u00e7\u00fck, orta ve b\u00fcy\u00fck boyutlardaki EVlerdeki HGSC ile ili\u015fkilendirilen proteinleri ara\u015ft\u0131rmak amac\u0131yla biyobelirte\u00e7lerin ke\u015ffi ve do\u011frulanmas\u0131nda kullan\u0131lan s\u0131v\u0131 kromatografisi-k\u00fctle spektrometresi y\u00f6ntemi uyguland\u0131.<\/p>\n

Analizlerde k\u00fc\u00e7\u00fck boyutlu EVlerdeki HGSC ile ili\u015fkilendirilen FR\u03b1, Claudin-3 ve TACSTD2 adl\u0131 \u00fc\u00e7 zar proteini bulundu.<\/p>\n

S\u00f6z konusu zar proteinlerinin yumurtal\u0131k kanserinin erken ve daha kolay te\u015fhisinde yard\u0131mc\u0131 olabilece\u011fi bildirildi.<\/p>\n

EVlerin kan \u00f6rneklerinden ayr\u0131\u015ft\u0131r\u0131lmas\u0131nda nanotel kullan\u0131ld\u0131<\/h3>\n

Nagoya \u00dcniversitesi M\u00fchendislik Fak\u00fcltesi’nde g\u00f6revli nanotel uzman\u0131 Dr. Takao Yasui, ara\u015ft\u0131rma i\u00e7in EVlerin kanser te\u015fhisine yard\u0131mc\u0131 olup olmad\u0131\u011f\u0131n\u0131 tespit etmek amac\u0131yla kan \u00f6rneklerinden ayr\u0131\u015ft\u0131r\u0131lmas\u0131nda kullan\u0131lmak \u00fczere polyketon zincirle kapl\u0131 nanotel \u00fcretti.<\/p>\n

Ara\u015ft\u0131rmac\u0131lardan Dr. Akira, EVlerin farkl\u0131 bir\u00e7ok molek\u00fclle y\u00fckl\u00fc olmas\u0131 nedeniyle daha k\u00fc\u00e7\u00fck EVlerin s\u00f6z konusu biyobelirte\u00e7leri tespit etmede daha uygun oldu\u011funu belirtti.<\/p>\n

Akira, ara\u015ft\u0131rma sonu\u00e7lar\u0131n\u0131n doktorlar\u0131n yumurtal\u0131k kanseri tedavilerinde ki\u015fiye \u00f6zel stratejiler geli\u015ftirmesinde de yard\u0131mc\u0131 olabilece\u011fine de i\u015faret etti.<\/p>\n

Ara\u015ft\u0131rma, “Science Advances” adl\u0131 dergide yay\u0131mland\u0131.<\/p>\n

Kaynak: AA<\/p>\n","protected":false},"excerpt":{"rendered":"

Japonya’da ara\u015ft\u0131rmac\u0131lar, yumurtal\u0131k kanserinin erken ve daha kolay te\u015fhis edilmesi i\u00e7in \u00e7al\u0131\u015fmalarda yard\u0131mc\u0131 olacak \u00fc\u00e7…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[100,4,17438],"tags":[],"class_list":["post-76367","post","type-post","status-publish","format-standard","hentry","category-gundem","category-saglik","category-yasam"],"views":85,"_links":{"self":[{"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/posts\/76367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/comments?post=76367"}],"version-history":[{"count":1,"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/posts\/76367\/revisions"}],"predecessor-version":[{"id":76369,"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/posts\/76367\/revisions\/76369"}],"wp:attachment":[{"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/media?parent=76367"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/categories?post=76367"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.haberegider.com\/blog\/wp-json\/wp\/v2\/tags?post=76367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}